In patients treated with surgery, survival rates were comparable for those aged 75 to 80 years and for younger patients<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b>
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FRIDAY, Sept. 12, 2025 (HealthDay News) — People aged 75 to 80 years at last screen who are diagnosed with screen-detected lung cancer (LC) have lower overall survival, but those undergoing surgery have no survival difference to younger patients, according to a study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer, held from Sept. 6 to 9 in Barcelona, Spain.<\/p>\n
Patrick Goodley, M.B.B.Chir., from Manchester University NHS Foundation Trust in the United Kingdom, and colleagues reported treatment and survival rates in people aged 75 to 80 years diagnosed with screen-detected LC in two targeted LC screening implementation settings in the United Kingdom: the Yorkshire Lung Screening Trial and North & East Manchester Lung Health Check program.<\/p>\n
The researchers identified 574 lung cancer cases, including 190 (33 percent) in those aged 75 to 80 years. There was no difference in stage distribution by age group. Overall, curative-intent treatment rates were high (87 percent), but older patients had a lower surgical resection rate (42 versus 58 percent in the 55- to 74-year-old age group). The older group also had higher all-cause mortality (hazard ratio, 1.54; 95 percent confidence interval, 1.12 to 2.10; P < 0.001), which was 44 versus 34 percent at four years from diagnosis. No survival difference was seen for the subgroup treated with surgery (hazard ratio, 1.00; 95 percent confidence interval, 0.47 to 2.11), with four-year mortality of 16 versus 18 percent (P = 1.00).<\/p>\n
“Our findings suggest that extending lung cancer screening up to age 80 could be valuable for older adults who are fit for surgery,” Goodley said in a statement.<\/p>\n