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THURSDAY, March 28, 2019 (HealthDay News) — Patients with type 2 diabetes are frailer than participants without diabetes, and frailty increases the risk for fragility fractures, according to a study published in the April issue of Diabetes Care<\/i>.<\/p>\n
Guowei Li, from Guangdong Second Provincial General Hospital in Guangzhou, China, and colleagues assessed whether frailty was associated with fracture risk and whether frailty could modify the propensity of type 2 diabetes toward an increased risk for fractures among a prospective cohort of 3,149 participants (70 percent women), 138 of whom had diabetes (60 percent women).<\/p>\n
The researchers found higher bone mineral density and Frailty Index (FI) scores in participants with diabetes versus controls. There was a significant relationship between FI score and the risk for incident fragility fractures (hazard ratios, 1.02 and 1.19 per-0.01 and per-0.10 FI increase, respectively). There was no evidence of interaction between frailty and diabetes for risk for hip and clinical spine fractures.<\/p>\n
“Frailty increases the risk of fragility fracture and enhances the effect of diabetes on fragility fractures. Particular attention should be paid to diabetes as a risk factor for fragility fractures in those who are frail,” the authors write.<\/p>\n
Several authors disclosed financial ties to the pharmaceutical industry, which provided funding for the study.<\/p>\n
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