{"id":17850,"date":"2019-03-18T00:00:00","date_gmt":"2019-03-18T00:00:00","guid":{"rendered":"http:\/\/medgoo.com\/index.php\/2019\/03\/18\/in-utero-ultrafine-particle-exposure-tied-to-asthma-in-offspring\/"},"modified":"2019-03-19T16:09:43","modified_gmt":"2019-03-19T16:09:43","slug":"in-utero-ultrafine-particle-exposure-tied-to-asthma-in-offspring","status":"publish","type":"post","link":"https:\/\/medgoo.com\/index.php\/2019\/03\/18\/in-utero-ultrafine-particle-exposure-tied-to-asthma-in-offspring\/","title":{"rendered":"In Utero Ultrafine Particle Exposure Tied to Asthma in Offspring"},"content":{"rendered":"<h3>Link independent of exposure to other air pollutants, including PM<sub>2.5<\/sub> and NO<sub>2<\/sub><\/h3>\n<p><b><\/b><\/p>\n<p><b><\/b><\/p>\n<p>MONDAY, March 18, 2019 (HealthDay News) &#8212; Exposure to ultrafine particles (UFPs; <0.1 \u03bcm) during the second trimester in utero is linked to the subsequent onset of asthma in children, according to a study published online Feb. 20 in the <i>American Journal of Respiratory and Critical Care Medicine<\/i>.<\/p>\n<p>Eric Lavigne, Ph.D., from Health Canada in Ottawa, and colleagues examined the association between prenatal and early postnatal life exposure to UFPs (single-pollutant and multipollutant models accounting for coexposures to PM<sub>2.5<\/sub> and NO<sub>2<\/sub>) and development of childhood asthma (up to age 6 years) among 160,641 singleton live births in the city of Toronto between April 1, 2006, and March 31, 2012.<\/p>\n<p>The researchers found that 27,062 children had an incident asthma diagnosis during the follow-up period. Second-trimester exposure to UFPs (hazard ratio [HR] per interquartile [IQR] increase, 1.09) was associated with asthma incidence after adjustment for other factors. After additional adjustment for PM<sub>2.5<\/sub> and NO<sub>2<\/sub>, UFP exposure during the second trimester of pregnancy remained positively associated with childhood asthma incidence (HR per IQR increase, 1.05).<\/p>\n<p>&#8220;These findings highlight the need for further research on the effects of UFPs during the perinatal period on respiratory health in children,&#8221; the authors write.<\/p>\n<p><a href=\"https:\/\/www.atsjournals.org\/doi\/pdf\/10.1164\/rccm.201810-1976OC\" target=\"_new\">Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n<p><i><\/i><\/p>\n<p><i>Copyright \u00a9 2019 <a href=\"https:\/\/www.healthday.com\/\" target=\"_new\">HealthDay<\/a>. All rights reserved.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Link independent of exposure to other air pollutants, including PM<sub>2.5<\/sub> and NO<sub>2<\/sub><\/p>\n","protected":false},"author":6,"featured_media":17870,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[11],"class_list":["post-17850","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"_links":{"self":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/17850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/comments?post=17850"}],"version-history":[{"count":0,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/17850\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media\/17870"}],"wp:attachment":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media?parent=17850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/categories?post=17850"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/tags?post=17850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}