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FRIDAY, March 15, 2019 (HealthDay News) — Overweight and obesity in adolescence is associated with an increased risk for developing renal cell carcinoma (RCC) later in life, according to a study published online Feb. 20 in the International Journal of Cancer<\/i>.<\/p>\n
Anna Landberg, from \u00d6rebro University in Sweden, and colleagues used data from a cohort of 238,788 Swedish men who underwent mandatory military conscription (1969 through 1976; mean age, 18.5 years) to evaluate the relationship between adolescent body mass index and subsequent risk for RCC. The Swedish Cancer Registry was used to identify incident diagnoses of RCC.<\/p>\n
The researchers found that 266 men were diagnosed with RCC during a follow-up of as long as 37 years. There was a trend noted for higher RCC risk with increasing body mass index (BMI) during adolescence, with a one-unit increase in BMI conferring a 6 percent increased risk for RCC. Men with overweight (BMI 25 to <30 kg\/m\u00b2) or obesity (BMI \u226530 kg\/m\u00b2) had hazard ratios for RCC of 1.76 and 2.87, respectively, versus normal-weight men (BMI 18.5 to <25 kg\/m\u00b2). No association was seen between RCC and indicators of childhood socioeconomic position or health status, blood pressure, erythrocyte sedimentation rate, cognitive function, or muscle strength as measured at conscription.<\/p>\n
“New data supporting a link between adolescent overweight\/obesity — alone and in combination with low physical working capacity — and renal cancer adds further important evidence supporting the implementation of early interventions within the rapidly growing group of overweight and obese teenagers,” a coauthor said in a statement.<\/p>\n