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Here are what the editors at HealthDay consider to be the most important developments in Neurology for January 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.<\/p>\n
Eye Tests Tied to Less Dementia in Older Drivers Who Crash<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Vision testing and in-person renewal requirements are significantly related to a reduced prevalence of dementia in older adults hospitalized after car crashes, according to a study published online Jan. 31 in Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Multifaceted Rehab Program Improves Balance in MS<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — For patients with multiple sclerosis (MS), a multifaceted vestibular-related rehabilitation program (Balance and Eye-Movement Exercises for Persons with Multiple Sclerosis [BEEMS]) is associated with improved outcomes, according to a study published online Jan. 31 in Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Survival Trends for Cancer Generally Increasing Worldwide<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Worldwide, survival trends for cancer are generally increasing, although there is considerable global variation in survival rates, according to a study published online Jan. 30 in The Lancet<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Non-Sleep Specialists May Offer Similar Quality Sleep Apnea Care<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Non-sleep specialists (NSSs) and sleep specialist physicians (SSPs) provide similar quality care with similar patient outcomes for adults with known or suspected obstructed sleep apnea (OSA), according to a review published online Jan. 30 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n TBI Linked to Increased Dementia Risk Over Several Years<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — Traumatic brain injury (TBI) is associated with persistently increased risk of dementia, according to a study published online Jan. 30 in PLOS Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Characteristics of Asymptomatic Paroxysmal A-Fib Identified<\/font><\/p>\n WEDNESDAY, Jan. 31, 2018 (HealthDay News) — For patients with paroxysmal atrial fibrillation (PAF), determinants of asymptomatic status have been identified, and mortality is increased for these patients, according to a study published in the December issue of CHEST<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text<\/a><\/p>\n Early Alzheimer’s Tied to Rest-Activity Rhythm Fragmentation<\/font><\/p>\n TUESDAY, Jan. 30, 2018 (HealthDay News) — Preclinical Alzheimer’s disease (AD) and aging are independently associated with rest-activity rhythm fragmentation among cognitively normal adults, according to a study published online Jan. 29 in JAMA Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Case Report: Fentanyl Use Associated With Amnesia<\/font><\/p>\n MONDAY, Jan. 29, 2018 (HealthDay News) — Another case of unusual amnestic syndrome that includes bilateral hippocampal lesions on magnetic resonance imaging has been described in a case report published online Jan. 30 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Regulators Trying to Reduce Physician Burden Linked to EHR<\/font><\/p>\n MONDAY, Jan. 29, 2018 (HealthDay News) — The Office of the National Coordinator for Health Information Technology (ONC) is trying to address some of the issues relating to physician electronic health record (EHR) burden, partly with the appointment of Don Rucker, M.D., who is skilled in informatics and board-certified in emergency and internal medicine, according to an article published in Medical Economics<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Specific White Matter Patterns Linked to Youth Psychopathology<\/font><\/p>\n MONDAY, Jan. 29, 2018 (HealthDay News) — General psychopathology is a heritable trait in youth that may be detected early in life through brain structural connectivity, according to a study published online Jan. 24 in JAMA Psychiatry<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial<\/a><\/p>\n Health Care Spending Up, Mainly Due to Rising Prices<\/font><\/p>\n MONDAY, Jan. 29, 2018 (HealthDay News) — Americans under age 65 years who were insured through their employer spent more than ever before on health care in 2016, with faster spending growth in 2016 than in recent years, according to the Health Care Cost Institute (HCCI)’s annual Health Care Cost and Utilization Report<\/i>.<\/p>\n More Information<\/a><\/p>\n 2016 Saw Increase in Birth Defects Potentially Linked to Zika<\/font><\/p>\n MONDAY, Jan. 29, 2018 (HealthDay News) — From the first half of 2016 to the second half of 2016, there was an increase in the number of birth defects potentially related to Zika virus infection, according to research published in the Jan. 26 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Viewpoint<\/a><\/p>\n Solanezumab Doesn’t Affect Cognitive Decline in Alzheimer’s<\/font><\/p>\n FRIDAY, Jan. 26, 2018 (HealthDay News) — For patients with mild Alzheimer’s disease, solanezumab administered every four weeks does not alter cognitive decline, according to a study published in the Jan. 25 issue of the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Review: Lower Cognitive Scores for HIV+, HIV-Exposed Children<\/font><\/p>\n FRIDAY, Jan. 26, 2018 (HealthDay News) — HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) children have lower cognitive and motor scores than HIV-unexposed and uninfected (HUU) children, according to a review published online Jan. 26 in Pediatrics<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Cannabidiol Efficacious for Lennox-Gastaut Drop Seizures<\/font><\/p>\n THURSDAY, Jan. 25, 2018 (HealthDay News) — For patients with drop seizures associated with Lennox-Gastaut syndrome, add-on cannabidiol is associated with a reduction in monthly drop seizure frequency, according to a study published online Jan. 24 in The Lancet<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Heart Disease, Stroke Risk Up Even Smoking 1 Cigarette\/Day<\/font><\/p>\n THURSDAY, Jan. 25, 2018 (HealthDay News) — Smoking one cigarette per day is still associated with a significant increased risk of coronary heart disease and stroke, according to research published online Jan. 24 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial<\/a><\/p>\n Significant Increase in Sleep Duration Reported for 2003-2016<\/font><\/p>\n THURSDAY, Jan. 25, 2018 (HealthDay News) — From 2003 to 2016 there was a significant increase in sleep duration on weekdays and weekends, according to a study published online Jan. 8 in SLEEP<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Multidomain Lifestyle Intervention May Aid Cognition in APOE<\/i> \u03b54 Carriers<\/font><\/p>\n THURSDAY, Jan. 25, 2018 (HealthDay News) — A multidomain lifestyle intervention seems to be beneficial for cognition in older at-risk individuals, even among apolipoprotein E (APOE<\/i>) \u03b54 carriers, according to a study published online Jan. 22 in JAMA Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Adjunct Zonisamide Beneficial in Dementia With Lewy Bodies<\/font><\/p>\n WEDNESDAY, Jan. 24, 2018 (HealthDay News) — For patients with dementia with Lewy bodies (DLB), zonisamide as an adjunct to levodopa therapy improves parkinsonism, according to a study published online Jan. 24 in Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Cognitive Training Aids Memory in People With Mild Impairment<\/font><\/p>\n WEDNESDAY, Jan. 24, 2018 (HealthDay News) — Cognitive training improves memory in older patients with mild cognitive impairment (MCI), according to a study published online Jan. 4 in the Journal of the American Geriatrics Society<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Closed-Head Injury May Induce TBI Even If No Concussive Sx<\/font><\/p>\n TUESDAY, Jan. 23, 2018 (HealthDay News) — Closed-head impact injuries can induce pathologic traumatic brain injury, independent of concussive signs, according to a study published online Jan. 18 in Brain<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Out-of-Pocket Expenditures Down With ACA Implementation<\/font><\/p>\n TUESDAY, Jan. 23, 2018 (HealthDay News) — Implementation of the Affordable Care Act (ACA) was associated with reduced out-of-pocket spending, although increases were noted in mean premium spending, according to a study published online Jan. 22 in JAMA Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n ADHD Meds Increasingly Prescribed to Reproductive-Aged Women<\/font><\/p>\n MONDAY, Jan. 22, 2018 (HealthDay News) — Reproductive-aged women are increasingly being prescribed attention-deficit\/hyperactivity disorder (ADHD) medications, according to research published in the Aug. 25 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Nutrients in Child’s First 1,000 Days Key for Neurodevelopment<\/font><\/p>\n MONDAY, Jan. 22, 2018 (HealthDay News) — The provision of adequate nutrients and healthy eating during a child’s first 1,000 days is important for optimal neurodevelopment, according to an American Academy of Pediatrics policy statement published online Jan. 22 in Pediatrics<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Pharmacist Participation in Stroke Response Cuts Door\u279cNeedle Time<\/font><\/p>\n FRIDAY, Jan. 19, 2018 (HealthDay News) — Having a pharmacist at bedside during acute ischemic stroke is associated with significantly shorter door-to-needle (DTN) times, according to a study published recently in the Annals of Pharmacotherapy<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Falls More Common in Elderly With Cognitive Impairment<\/font><\/p>\n THURSDAY, Jan. 18, 2018 (HealthDay News) — Increasing evidence shows that cognitive therapies may help reduce falls in older adults, according to a review published online Jan. 10 in the Journal of the American Geriatrics Society<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text (subscription or payment may be required)<\/a><\/p>\n Professionals Disagree About Asking Patients About Sexuality<\/font><\/p>\n THURSDAY, Jan. 18, 2018 (HealthDay News) — National Health Service (NHS) England recently recommended that professionals ask all patients their sexual orientation at every opportunity, although opinions are divided on whether this is appropriate, according to an article published online Jan. 17 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Onabotulinum Toxin-A Can Safely Improve Sleep Bruxism<\/font><\/p>\n THURSDAY, Jan. 18, 2018 (HealthDay News) — Onabotulinum toxin-A (BoNT-A) injections can improve sleep bruxism, according to a study published online Jan. 17 in Neurology<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text<\/a><\/p>\n Alzheimer’s Disease Variants Linked to Brain Amyloidosis<\/font><\/p>\n WEDNESDAY, Jan. 17, 2018 (HealthDay News) — Certain Alzheimer’s disease (AD) risk variants are associated with brain amyloidosis, according to a study published online Jan. 16 in JAMA Neurology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Brain Is Susceptible to Acute MI, Chronic Heart Failure<\/font><\/p>\n WEDNESDAY, Jan. 17, 2018 (HealthDay News) — Acute myocardial infarction (MI) and chronic heart failure have effects on the brain, according to a study published in the Jan. 23 issue of the Journal of the American College of Cardiology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Speech Outcomes Can Be Predicted After Cochlear Implant<\/font><\/p>\n WEDNESDAY, Jan. 17, 2018 (HealthDay News) — Brain areas unaffected by auditory deprivation can predict speech outcomes after cochlear implant (CI) in children, according to a study published online Jan. 15 in the Proceedings of the National Academy of Sciences of the United States of America<\/i>.<\/p>\n Abstract<\/a><\/p>\n Full Text (subscription or payment may be required)<\/a><\/p>\n Deep Brain Stimulation Tied to Improved Symptoms in Tourette<\/font><\/p>\n TUESDAY, Jan. 16, 2018 (HealthDay News) — For patients with Tourette syndrome, deep brain stimulation (DBS) is associated with symptomatic improvement but also some important adverse events, according to a study published online Jan. 16 in JAMA Neurology<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Increased Risk of Thrombosis in Myeloproliferative Neoplasms<\/font><\/p>\n TUESDAY, Jan. 16, 2018 (HealthDay News) — Patients with myeloproliferative neoplasms (MPNs) have increased risk of arterial thrombosis and venous thrombosis across all age groups and MPN subtypes, according to a study published online Jan. 16 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Sauna Exposure Improves Cardiovascular Function<\/font><\/p>\n TUESDAY, Jan. 16, 2018 (HealthDay News) — Sauna exposure is associated with improvements in cardiovascular function and arterial compliance, according to a study published online Dec. 21 in the Journal of Human Hypertension<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Treatment of Urgency Urinary Incontinence Aids Sleep Quality<\/font><\/p>\n FRIDAY, Jan. 12, 2018 (HealthDay News) — Pharmacologic treatment of urgency urinary incontinence (UUI) improves sleep quality, according to research published online Jan. 9 in Obstetrics & Gynecology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n AMA Online Tools Address Systems-Level Physician Burnout<\/font><\/p>\n THURSDAY, Jan. 11, 2018 (HealthDay News) — Tools and resources have been developed to help address physician burnout at the systems level, which may affect more than half of doctors, according to a report published by the American Medical Association (AMA).<\/p>\n More Information<\/a><\/p>\n Closure of Patent Foramen Ovale Cuts Recurrent Stroke\/TIA Risk<\/font><\/p>\n THURSDAY, Jan. 11, 2018 (HealthDay News) — Percutaneous and transcatheter patent foramen ovale (PFO) closure prevent recurrent stroke in adults with PFO and cryptogenic stroke, according to two reviews published online Jan. 9 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text – De Rosa (subscription or payment may be required)<\/a><\/p>\n Abstract\/Full Text – Shah (subscription or payment may be required)<\/a><\/p>\n Neurodevelopment Not Impacted by Glucocorticoids in Preemies<\/font><\/p>\n WEDNESDAY, Jan. 10, 2018 (HealthDay News) — Use of inhaled glucocorticoids in extremely preterm infants for the prevention of bronchopulmonary dysplasia does not lead to a higher rate of neurodevelopmental disability at 2 years, according to a study published in the Jan. 11 issue of the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Economic Impact of Physicians Quantified for 2015<\/font><\/p>\n WEDNESDAY, Jan. 10, 2018 (HealthDay News) — Physicians have a large economic impact across the nation, creating an aggregate of $2.3 trillion of economic activity and supporting employment of nearly 12.6 million Americans, according to a report published by the American Medical Association.<\/p>\n More Information<\/a><\/p>\n Vitamin D3<\/sub> Improves Arterial Stiffness in Dose-Response Way<\/font><\/p>\n WEDNESDAY, Jan. 10, 2018 (HealthDay News) — For overweight African-Americans with vitamin D deficiency, arterial stiffness is improved by vitamin D3<\/sub> supplementation in a dose-response manner, according to a study published online Dec. 7 in PLOS ONE<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Idalopirdine May Not Improve Cognition in Mild Alzheimer’s<\/font><\/p>\n TUESDAY, Jan. 9, 2018 (HealthDay News) — The use of idalopirdine does not improve cognition versus placebo over 24 weeks of treatment for patients with mild-to-moderate Alzheimer’s disease (AD), according to research published in the Jan. 9 issue of the Journal of the American Medical Association<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Follow-Up Delta CHA2<\/sub>DS2<\/sub>-VASc Score Better Predicts CVA in A-Fib<\/font><\/p>\n TUESDAY, Jan. 9, 2018 (HealthDay News) — Assessing change in the CHA2<\/sub>DS2<\/sub>-VASc score over time is more predictive of ischemic stroke in patients with atrial fibrillation (AF) than the baseline score, according to a study published in the Jan. 16 issue of the Journal of the American College of Cardiology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Mental Disorders Common in Kids With Chronic Physical Conditions<\/font><\/p>\n TUESDAY, Jan. 9, 2018 (HealthDay News) — Children with a physical condition frequently have a mental disorder, which impacts quality of life, according to a study published in the January issue of BMJ Open<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Rituximab Tops Other Disease-Modifying Tx Options in MS<\/font><\/p>\n TUESDAY, Jan. 9, 2018 (HealthDay News) — Rituximab has better efficacy and lower discontinuation rates than other disease-modifying treatment (DMT) choices for newly diagnosed relapsing-remitting multiple sclerosis (RRMS), according to a study published online Jan. 8 in JAMA Neurology<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Pain Self-Efficacy Questionnaire Helps to Evaluate Migraine Pain<\/font><\/p>\n MONDAY, Jan. 8, 2018 (HealthDay News) — The Pain Self-Efficacy Questionnaire (PSEQ) successfully demonstrates the extent of debility in migraine surgery patients and puts migraine pain in perspective within the realm of other known pain conditions, according to a study published in the January issue of Plastic and Reconstructive Surgery<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Maternal Folic Acid, Multivitamin Use May Cut ASD Risk in Offspring<\/font><\/p>\n MONDAY, Jan. 8, 2018 (HealthDay News) — The risk of autism spectrum disorder (ASD) is reduced in offspring with maternal exposure to folic acid and multivitamin supplementation before and during pregnancy, according to a study published online Jan. 3 in JAMA Psychiatry<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Physicians Frequently Continue to Work While Ill<\/font><\/p>\n FRIDAY, Jan. 5, 2018 (HealthDay News) — Many physicians continue working and caring for patients while they are sick, according to an article published in Medical Economics<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Closed-Loop Neurotechnology Improves PTSD Symptoms<\/font><\/p>\n FRIDAY, Jan. 5, 2018 (HealthDay News) — Service members and veterans show reductions in post-traumatic stress (PTS) symptomatology, insomnia, depression, and anxiety with use of high-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), a closed-loop, allostatic, acoustic stimulation neurotechnology, according to a study published online Dec. 22 in Military Medical Research<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Transcranial Direct Current Stimulation Promising for Bipolar<\/font><\/p>\n FRIDAY, Jan. 5, 2018 (HealthDay News) — Transcranial direct current stimulation (tDCS) appears to be effective and safe as an add-on intervention for adults with bipolar depression, according to a study published online Dec. 27 in JAMA Psychiatry<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Cancer Death Rate Continuing to Decline in United States<\/font><\/p>\n FRIDAY, Jan. 5, 2018 (HealthDay News) — In both men and women in the United States, the cancer death rate declined by about 1.5 percent annually from 2006 to 2015, according to a study published online Jan. 4 in CA: A Cancer Journal for Clinicians<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n KRAS<\/i> Mutations Linked to Brain Arteriovenous Malformations<\/font><\/p>\n FRIDAY, Jan. 5, 2018 (HealthDay News) — Many patients with arteriovenous malformations of the brain have somatic activating KRAS<\/i> mutations, according to a study published online Jan. 3 in the New England Journal of Medicine<\/i>.<\/p>\n Abstract<\/a><\/p>\n