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FRIDAY, Feb. 8, 2019 (HealthDay News) — Hospitalization for vaccine-preventable infections occurs in more than 15 percent of pediatric solid organ transplant recipients in the first five years after surgery, according to a study recently published in JAMA Pediatrics<\/i>.<\/p>\n
Amy G. Feldman, M.D., from Children’s Hospital Colorado in Denver, and colleagues used data from the Pediatric Health Information System to assess hospitalizations for vaccine-preventable infections among 6,980 patients (mean age at transplant, 8 years) in the first five years after pediatric solid organ transplant.<\/p>\n
The researchers found a total of 1,490 cases of vaccine-preventable infections among 1,092 patients (15.6 percent). Of these cases, 13.1 percent occurred during transplant hospitalization. Transplant hospitalizations complicated by vaccine-preventable infections were $120,498 more expensive than those not complicated by vaccine-preventable infections. For all infections, the case fatality rate was 1.7 percent. Increased risk for hospitalization from a vaccine-preventable infection was positively associated with age <2 years at time of transplant as well as receipt of a lung, heart, intestine, or multivisceral organ.<\/p>\n
“There was significant morbidity, mortality, and costs from these infections, demonstrating the importance of immunizing all transplant candidates and recipients,” the authors write.<\/p>\n
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