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MONDAY, March 5, 2018 (HealthDay News) — Adolescents smoking electronic-cigarettes (e-cigarettes) only have significantly higher excretion of volatile organic chemical compounds than non-smokers, although the levels are lower than among those using cigarettes in addition to e-cigarettes, according to a study published online March 5 in Pediatrics<\/i>.<\/p>\n
Mark L. Rubinstein, M.D., from the University of California in San Francisco, and colleagues examined the presence of chemical toxicants associated with e-cigarette use among adolescents (average age, 16.4 years). Adolescent e-cigarette users were divided into e-cigarette-only users (no cigarettes in past 30 days; 67 participants), dual users (use of cigarettes in addition to e-cigarettes in past 30 days; 16 participants), and never-using controls (20 participants). Saliva was obtained within the past 24 hours of e-cigarette use and urine was collected for analysis of 4-[methylnitrosamino]-1-[3-pyridyl]-1-butanol and eight volatile organic chemical compounds.<\/p>\n
The researchers found that, compared with e-cigarette-only users, dual users had significantly higher urine excretion of metabolites of benzene, ethylene oxide, acrylonitrile, acrolein, and acrylamide (all P < 0.05). Compared with controls, e-cigarette-only users had significantly higher excretion of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide, and crotonaldehyde (all P < 0.05).<\/p>\n
“Messaging to teenagers should include warnings about the potential risk from toxic exposure to carcinogenic compounds generated by these products,” the authors write.<\/p>\n
Several authors disclosed financial ties to companies that market medications to aid smoking cessation and manufacture tobacco cessation devices; one author has served as a paid expert witness in litigation against tobacco companies.<\/p>\n
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