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FRIDAY, Dec. 21, 2018 (HealthDay News) — Among patients with obstructive sleep apnea, older age and reduced body mass index (BMI) are predictors of upper airway stimulation (UAS) treatment response, according to a study published online Nov. 28 in the European Respiratory Journal<\/i>.<\/p>\n
Clemens Heiser, M.D., from Munich Technical University in Germany, and colleagues sought to identify predictors of UAS therapy response in a multicenter registry of 508 patients who underwent UAS implantation in the United States and Germany between October 2016 and January 2018.<\/p>\n
The researchers found that the median apnea\/hypopnea index reduced from 34 to seven events\/hour\u22121<\/sup>, while the median Epworth sleepiness scale score reduced from 12 to 7 from baseline to 12 months postimplant. For each one-year increase in age, there was a 4 percent increase in the odds of treatment success in post hoc analyses, while there was 9 percent reduced odds of treatment success for each one-unit increase in BMI. Age persisted as a statistically significant predictor of treatment success in multivariable analyses.<\/p>\n “In this largest international report to date, we have for the first time identified ways to predict who will be successfully treated with this obstructive sleep apnea treatment,” a coauthor said in a statement.<\/p>\n Several authors disclosed financial ties to the medical device industry.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n