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THURSDAY, Nov. 29, 2018 (HealthDay News) — For individuals with obstructive sleep apnea (OSA) treated with an optimally titrated mandibular advancement splint, normalization of the respiratory effort index derived from vertical mandibular movements (MM-REI) reflects the efficacy of the appliance, according to a study published online Nov. 6 in CHEST<\/i>.<\/p>\n
Jean-Benoit Martinot, M.D., from the CHU UCL Namur Site Sainte-Elisabeth in Belgium, and colleagues examined the effectiveness of mandibular advancement splint therapy using MM-REI compared with the apnea-hypopnea index (AHI) and oxygen desaturation index (ODI). Fifty-six participants with OSA were treated with a custom mandibular splint. Participants were evaluated at the end of the titration procedure when snoring was reported as absent by the sleep partner.<\/p>\n
The researchers found that all indices of OSA severity were decreased at the end of titration versus baseline: \u221248.9 to \u221271.1 percent; ODI, \u221249.5 to \u221277.2 percent; the largest responses were seen for the obstructive hypopnea index (\u221270.6 to \u221288.5 percent) and MM-REI (\u221269.5 to \u221296.3 percent). The efficacy of the appliance was accurately reflected by MM-REI normalization via reductions in both mandibular movement event rate and duration.<\/p>\n
“Analysis of mandibular movements provides useful information about the effects of oral appliance therapy titration once snoring in subjects with mild-to-moderate OSA is reported absent,” the authors write.<\/p>\n
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