{"id":13099,"date":"2018-11-20T00:00:00","date_gmt":"2018-11-20T00:00:00","guid":{"rendered":"http:\/\/medgoo.com\/index.php\/2018\/11\/20\/prenatal-nitric-oxide-exposure-linked-to-higher-risk-for-autism\/"},"modified":"2018-11-21T17:00:11","modified_gmt":"2018-11-21T17:00:11","slug":"prenatal-nitric-oxide-exposure-linked-to-higher-risk-for-autism","status":"publish","type":"post","link":"https:\/\/medgoo.com\/index.php\/2018\/11\/20\/prenatal-nitric-oxide-exposure-linked-to-higher-risk-for-autism\/","title":{"rendered":"Prenatal Nitric Oxide Exposure Linked to Higher Risk for Autism"},"content":{"rendered":"<h3>No significant link seen for ASD risk and exposure to particulate matter (PM)<sub>2.5<\/sub>, nitrogen dioxide<\/h3>\n<p><b><\/b><\/p>\n<p><b><\/b><\/p>\n<p>TUESDAY, Nov. 20, 2018 (HealthDay News) &#8212; Prenatal exposure to nitric oxide (NO) is associated with an increased risk for autism spectrum disorder (ASD), according to a study published online Nov. 19 in <i>JAMA Pediatrics<\/i>.<\/p>\n<p>Lief Pagalan, from Simon Fraser University in Vancouver, British Columbia, Canada, and colleagues examined the correlation between prenatal exposures to airborne pollutants and ASD in a population-based cohort encompassing nearly all births in Metro Vancouver from 2004 through 2009, with follow-up through 2014.<\/p>\n<p>The researchers found that 1.0 percent of children were diagnosed with ASD by the age of 5 years in a cohort of 132,256 births. There was no significant correlation between exposure to particulate matter with a diameter less than 2.5 \u00b5m (PM<sub>2.5<\/sub>) in pregnancy and the likelihood of ASD (adjusted odds ratio [aOR] per interquartile range, 1.04 [95 percent confidence interval (CI), 0.98 to 1.10] per 1.5 \u00b5\/m\u00b3 increase) or for exposure to nitrogen dioxide (NO<sub>2<\/sub>; aOR, 1.06 [95 percent CI, 0.99 to 1.12] per 4.8 ppb increase); for NO, the odds ratio was significant (aOR, 1.07 [95 percent CI, 1.01 to 1.13] per 10.7 ppb increase). For male children, the corresponding odds ratios were 1.04 (95 percent CI, 0.98 to 1.10) for PM<sub>2.5<\/sub>, 1.09 (95 percent CI, 1.02 to 1.15) for NO, and 1.07 (95 percent CI, 1.00 to 1.13) for NO<sub>2<\/sub>. For female children, the corresponding odds ratios were 1.03 (95 percent CI, 0.90 to 1.18), 0.98 (95 percent CI, 0.83 to 1.13), and 1.00 (95 percent CI, 0.86 to 1.16).<\/p>\n<p>&#8220;Reducing exposures of pregnant women to environmental nitric oxide may be associated with a reduction in autism spectrum disorder incidence in their children,&#8221; the authors write.<\/p>\n<p><a href=\"https:\/\/jamanetwork.com\/journals\/jamapediatrics\/article-abstract\/2714386\" target=\"_new\">Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n<p><i><\/i><\/p>\n<p><i>Copyright \u00a9 2018 <a href=\"https:\/\/www.healthday.com\/\" target=\"_new\">HealthDay<\/a>. All rights reserved.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>No significant link seen for ASD risk and exposure to particulate matter (PM)<sub>2.5<\/sub>, nitrogen dioxide<\/p>\n","protected":false},"author":6,"featured_media":13131,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[11],"class_list":["post-13099","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"_links":{"self":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/13099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/comments?post=13099"}],"version-history":[{"count":0,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/13099\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media\/13131"}],"wp:attachment":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media?parent=13099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/categories?post=13099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/tags?post=13099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}