Medium and high T2DM genetic risk not linked to increased risk for ASCVD when TV viewing is no more than one hour\/day<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b>
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WEDNESDAY, March 12, 2025 (HealthDay News) — Medium and high type 2 diabetes (T2D) genetic risks are not associated with an increased risk for atherosclerotic cardiovascular disease (ASCVD) when television viewing is no more than one hour a day, according to a study published online March 12 in the Journal of the American Heart Association<\/em>.<\/p>\n Mengyao Wang, Ph.D., from The University of Hong Kong Li Ka Shing Faculty of Medicine, and colleagues examined the interaction between watching television and T2D genetic risk for ASCVD in a study involving 346,916 White British individuals from the U.K. Biobank. Based on 138 genetic variants associated with T2D, a weighted polygenic risk score was calculated for T2D. Time spent watching television was self-reported and categorized as no more than one hour\/day and two or more hours\/day. A total of 21,265 incident ASCVD events were identified during a median follow-up of 13.8 years.<\/p>\n The researchers found that watching television for two or more hours\/day <\/strong>was associated with a 12 percent increased risk for ASCVD compared with no more than one hour\/day, independent of T2D genetic risk. As long as television viewing was no more than one hour\/day, medium and high T2D genetic risk was not associated with higher risks for ASCVD. For multiplicative and additive interactions between T2D genetic risk and television viewing, the P values were 0.050 and 0.038, respectively. The 10-year absolute ASCVD risk was lower for high T2D genetic risk plus no more than one hour\/day television viewing versus low T2D genetic risk plus two or more hours\/day television viewing (2.13 versus 2.46 percent).<\/p>\n “We found that people with high genetic risk for type 2 diabetes may exhibit lower chances of developing atherosclerotic cardiovascular disease by limiting TV watching to one hour or less each day,” Wang said in a statement. “This suggests that less TV viewing could serve as a key behavioral target for preventing atherosclerotic cardiovascular diseases linked to type 2 diabetes genetics.”<\/p>\n