Higher stress as a discrete measure and moderate stress associated with CIS in women, but not in men<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b>
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MONDAY, March 10, 2025 (HealthDay News) — Self-perceived stress is associated with cryptogenic ischemic stroke (CIS), according to a study published online March 5 in Neurology<\/em>.<\/p>\n Shakar Kutal, from the Helsinki University Hospital, and colleagues explored the association between self-perceived stress and CIS in a study involving young patients aged 18 to 49 years with a first-ever CIS and sex- and age-matched stroke-free controls from 19 European centers (426 patients and 426 controls). A modified version of the Perceived Stress Scale (PSS) was used to assess self-perceived stress.<\/p>\n The researchers found that compared with controls, patients were more often at least moderately stressed (46.2 versus 33.3 percent). Higher self-perceived stress as a discrete measure was independently associated with CIS in the entire study population. There was an independent association seen between moderate stress and CIS in a categorical PSS score analysis; no independent association was seen with high stress. In women, but not in men, higher stress as a discrete measure was associated with CIS. Moderate stress was also associated with CIS in women, but not in men. Higher stress as a discrete measure was associated with CIS only in those aged 18 to 39 years when the patients were stratified by age.<\/p>\n “Given the potential importance of CIS in the context of early-onset strokes, understanding the role of self-perceived stress in this population may be crucial for developing more effective prevention strategies,” the authors write.<\/p>\n One author disclosed financial ties to Janssen.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n