Risk for PSE was lower for patients treated with ARBs and higher for those receiving calcium channel blockers, beta-blockers<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b>
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TUESDAY, Dec. 17, 2024 (HealthDay News) — For patients with hypertension and ischemic stroke, the risk for poststroke epilepsy (PSE) varies according to antihypertensive treatment, according to a study presented at the annual meeting of the American Epilepsy Society, held from Dec. 6 to 10 in Los Angeles.<\/p>\n
Giacomo Evangelista, M.D., Ph.D., from the “G. d’Annunzio” University of Chieti-Pescara in Italy, and colleagues examined the effectiveness of antihypertensive treatment in preventing PSE in a retrospective, observational study. Patients with hypertension and diagnosis of ischemic stroke were retrospectively selected; all participants were followed up for PSE at a mean of 66 months.<\/p>\n
The researchers found that 38 of the 528 patients (7.2 percent) developed PSE. The risk for PSE development was higher in association with anterior cerebral artery involvement and cortico-sottocortical lesions. The risk for PSE was lower in patients treated with angiotensin receptor blockers, while incidence was higher for those receiving calcium channel blockers and beta-blockers. No differences were seen for angiotensin-converting enzyme inhibitor use.<\/p>\n
“These findings highlight the importance of personalized medicine, particularly in managing blood pressure in stroke patients,” co-lead author Fedele Dono, M.D., also from G. d’Annunzio University of Chieti-Pescara, said in a statement. “Further research in more patients is necessary to confirm these findings and explore the underlying mechanisms in more detail.”<\/p>\n