Neighborhood disadvantage tied to higher blood pressure and cardiometabolic index, as well as lower cognitive scores<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b>
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FRIDAY, Dec. 13, 2024 (HealthDay News) — Neighborhood disadvantage is more strongly associated with measures of cardiometabolic health and cognition in individuals without mild cognitive impairment (MCI) compared to those with MCI, according to a study published online Dec. 6 in Alzheimer\u2019s & Dementia: Diagnosis, Assessment & Disease Monitoring<\/em>.<\/p>\n Sudarshan Krishnamurthy, from the Wake Forest University School of Medicine in Winston-Salem, North Carolina, and colleagues investigated the relationship between neighborhood disadvantage with measures of cardiometabolic health and cognition. Analysis included 537 adults (aged >55 years) participating in the Wake Forest Alzheimer’s Disease Research Center Healthy Brain Study (between 2016 and 2021); 39.3 percent had MCI.<\/p>\n The researchers found that Area Deprivation Index (ADI) was positively associated with blood pressure and cardiometabolic index (CMI). There was a negative association between ADI and global and Preclinical Alzheimer’s Cognitive Composite scores in cognitively unimpaired individuals. In individuals with MCI, ADI was only positively associated with hemoglobin A1c.<\/p>\n “Neighborhood disadvantage is associated more strongly with measures of cardiometabolic health and cognition among cognitively unimpaired individuals rather than MCI,” the authors write. “These findings demonstrate a need for structural solutions to address social determinants of health in an attempt to reduce cardiometabolic and cognitive risks.”<\/p>\n One author disclosed ties to the biopharmaceutical industry.<\/p>\n