Findings seen for cockroach and mouse allergens<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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WEDNESDAY, Sept. 25, 2024 (HealthDay News) — Cockroach and mouse allergen exposure may predispose children with asthma to upper respiratory infections (URIs) and worse respiratory outcomes, according to a study published online Aug. 19 in the\u00a0Journal of Allergy and Clinical Immunology<\/em>.<\/p>\n Darlene Bhavnani, Ph.D., from the University of Texas at Austin, and colleagues examined associations between indoor allergens and: URI, URI + cold symptoms, URI + cold symptoms + pulmonary eosinophilic inflammation (fraction of exhaled nitric oxide \u00e2\u0089\u00a520 ppb), and URI + cold symptoms + reduced lung function (percent predicted forced expiratory volume in 1 second of <80 percent). The analysis included data from 90 participants in the Environmental Control as Add-on Therapy for Childhood Asthma study (192 observations).<\/p>\n The researchers found that 27 percent of observations were positive for URI. There were increased odds of a URI with cold symptoms with a doubling in cockroach allergen concentration (odds ratio [OR], 1.18; 95 percent confidence interval [CI], 0.99 to 1.40), as well as higher odds of a URI + cold symptoms + pulmonary eosinophilic inflammation (OR, 1.31; 95 percent CI, 1.10 to 1.57) and URI + cold symptoms + reduced lung function (OR, 1.45; 95 percent CI, 1.13 to 1.85). There were positive associations between mouse allergen concentrations and all outcomes. Among children sensitized to pest allergens, associations were suggestively stronger.<\/p>\n “These results could help explain why some children, especially those who live in underserved areas, have more trouble with their asthma than others,” Bhavnani said in a statement.<\/p>\n Abstract\/Full Text\u00a0(subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n