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Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for September 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.<\/p>\n
Physicians Often Don’t Address Their Burnout<\/font><\/p>\n FRIDAY, Sept. 28, 2018 (HealthDay News) — More than half of physicians experience burnout, and many do not seek treatment for burnout, according to a report published in the American Medical Association’s AMA Wire<\/i>.<\/p>\n More Information<\/a><\/p>\n Handheld Device Inspired by Star Trek May Allow Rapid Diagnosis<\/font><\/p>\n FRIDAY, Sept. 28, 2018 (HealthDay News) — A device inspired by the Star Trek famous tricorder device pairs a handheld sensor with a smartphone app to measure the levels of various metabolites associated with multiple diseases in fluid samples from patients, according to a report published in an upcoming issue of Biosensors and Bioelectronics<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Business Degree Increasingly Useful for Doctors<\/font><\/p>\n THURSDAY, Sept. 27, 2018 (HealthDay News) — Having a Master of Business Administration degree (M.B.A.) can help doctors with important, practice-related decisions, according to a report published recently in Physician Practice<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Newer Hormonal Contraception May Cut Ovarian Cancer Risk<\/font><\/p>\n THURSDAY, Sept. 27, 2018 (HealthDay News) — There is a reduction in ovarian cancer risk associated with use of contemporary combined hormonal contraceptives, according to a study published online Sept. 26 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Single Agent Treats Two Cancers With Same Genetic Cause<\/font><\/p>\n THURSDAY, Sept. 27, 2018 (HealthDay News) — A single checkpoint inhibitor can be used to successfully treat two simultaneous types of primary cancer in a patient with Lynch syndrome, according to a research letter published online Sept. 25 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Practices Should Set Rules for Staff Social Media Use<\/font><\/p>\n THURSDAY, Sept. 27, 2018 (HealthDay News) — Medical practices can take steps to avoid problems related to use of social media by staff members, according to an article published in Medical Economics<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Burnout, Career Choice Regret Prevalent in U.S. Residents<\/font><\/p>\n WEDNESDAY, Sept. 26, 2018 (HealthDay News) — Symptoms of burnout and career choice regret are prevalent among U.S. resident physicians, according to a study published in the Sept. 18 issue of the Journal of the American Medical Association<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Many Countries Failing on Non-Communicable Dz Death Targets<\/font><\/p>\n WEDNESDAY, Sept. 26, 2018 (HealthDay News) — Many countries are falling short on targets to reduce mortality from non-communicable diseases (NCDs), according to a study published in the Sept. 22 issue of The Lancet<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Persistent Post-Op Opioid Use in Young Cancer Patients Explored<\/font><\/p>\n WEDNESDAY, Sept. 26, 2018 (HealthDay News) — Higher inpatient pain scores and postoperative opioid consumption are associated with persistent opioid use of up to six months among children and adolescents who have undergone cytoreductive surgery with hyperthermic intraperitoneal chemotherapy, according to a study published in a recent issue of Pediatric Anesthesia<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Cancer-Related Gene Variations Frequently Reclassified<\/font><\/p>\n TUESDAY, Sept. 25, 2018 (HealthDay News) — Among individuals undergoing hereditary cancer testing, some variants of uncertain significance are reclassified, with almost one-quarter of those variants reclassified at a single commercial laboratory, according to a study published in the Sept. 25 issue of the Journal of the American Medical Association<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial 1 (subscription or payment may be required)<\/a><\/p>\n Editorial 2 (subscription or payment may be required)<\/a><\/p>\n Critics Demand Stop to ‘Guinea Pig’ Sepsis Clinical Trial<\/font><\/p>\n TUESDAY, Sept. 25, 2018 (HealthDay News) — A major non-profit advocacy group is asking that a large government trial comparing treatments for sepsis be shut down.<\/p>\n The New York Times<\/i> Article<\/a><\/p>\n Clovers Clinical Trial<\/a><\/p>\n Physician-Group ACOs Generate Medicare Savings<\/font><\/p>\n TUESDAY, Sept. 25, 2018 (HealthDay News) — Physician-group accountable care organizations (ACOs) participating in the Medicare Shared Savings Program (MSSP) generated significantly more savings for Medicare that grew from 2012 to 2015 compared with hospital-integrated ACOs, according to research published in the Sept. 20 issue of the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n In 2016, Proportion of Uninsured Americans Down to 10 Percent<\/font><\/p>\n TUESDAY, Sept. 25, 2018 (HealthDay News) — From 2013 to 2016 there was a reduction in uninsurance among Americans from 17 to 10 percent, according to a report published in September by the Robert Wood Johnson Foundation (RWJF) and the Urban Institute.<\/p>\n More Information<\/a><\/p>\n Novel Immunotherapy May Up Survival in Melanoma Brain Mets<\/font><\/p>\n TUESDAY, Sept. 25, 2018 (HealthDay News) — Checkpoint blockade immunotherapy (CBI) is associated with significant increases in overall survival (OS) in a real-world population of patients undergoing treatment for melanoma brain metastases (MBM), according to research published in the September issue of Cancer Immunology Research<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Net Benefit of Anticoagulants for A-Fib Varies With Stroke Rate<\/font><\/p>\n MONDAY, Sept. 24, 2018 (HealthDay News) — There is variation in the net clinical benefit of anticoagulants based on variation in published atrial fibrillation (AF) stroke rates, according to a study published online Sept. 25 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Most Breast Cancer Diagnoses Given Over the Phone<\/font><\/p>\n MONDAY, Sept. 24, 2018 (HealthDay News) — Currently, most patients receiving a breast cancer diagnosis receive the information over the phone, according to a study published online Aug. 7 in Supportive Care in Cancer<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Some Clinicians, Patients Record Clinic Visits for Patient Use<\/font><\/p>\n FRIDAY, Sept. 21, 2018 (HealthDay News) — A considerable proportion of clinicians and patients report having recorded a clinic visit for the patient’s personal use, according to a study published in the September issue of the Journal of Medical Internet Research<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Dozens of Medical Groups Join Forces to Improve Diagnoses<\/font><\/p>\n FRIDAY, Sept. 21, 2018 (HealthDay News) — Every nine minutes, a patient in a U.S. hospital dies because a diagnosis was wrong or delayed — resulting in 80,000 deaths a year. That sobering estimate comes from the Society to Improve Diagnosis in Medicine (SIDM).<\/p>\n More Information<\/a><\/p>\n Promising New Way to Identify Breast Cancer Tumors<\/font><\/p>\n FRIDAY, Sept. 21, 2018 (HealthDay News) — Molecular markers of breast cancer tumors can be identified by focusing on parameters of a cell’s nucleus, and aided by machine learning, according to a study published online Sept. 4 in npj Breast Cancer<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Sensitivity for CRC Detection Up With Decreasing FIT Threshold<\/font><\/p>\n FRIDAY, Sept. 21, 2018 (HealthDay News) — Programmatic sensitivity for colorectal cancer (CRC) detection increases modestly with decreasing fecal immunochemical test (FIT) positivity thresholds, according to a study published online Sept. 18 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Research Links Doctor Burnout to Patient Safety Incidents<\/font><\/p>\n THURSDAY, Sept. 20, 2018 (HealthDay News) — Physician burnout is associated with increased risk of patient safety incidents, poorer quality of care due to low professionalism, and reduced patient satisfaction, according to a review published online Sept. 4 in JAMA Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Crowdfunding for Cancer Tx Could Exploit Vulnerable Patients<\/font><\/p>\n THURSDAY, Sept. 20, 2018 (HealthDay News) — There are fears that huge sums are being raised on crowdfunding sites for alternative cancer treatments that are not backed by evidence, according to a feature article published online Sept. 12 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Hospitals Charge 479 Percent of Cost of Drugs on Average<\/font><\/p>\n THURSDAY, Sept. 20, 2018 (HealthDay News) — On average, hospitals mark up drugs by 479 percent of their cost, according to a report from The Moran Company, commissioned by the Pharmaceutical Research and Manufacturers of America (PhRMA).<\/p>\n More Information<\/a><\/p>\n Cardiac Monitoring Needed for High-Risk Breast Cancer Patients<\/font><\/p>\n THURSDAY, Sept. 20, 2018 (HealthDay News) — Risk of cardiotoxicity is higher for patients receiving trastuzumab and\/or anthracyclines for the treatment of breast cancer, according to a study published in the Aug. 1 issue of JACC: Cardiovascular Imaging<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Residents Should Take Advantage of Paid Time Off<\/font><\/p>\n THURSDAY, Sept. 20, 2018 (HealthDay News) — Although there are many demands on residents, taking advantage of paid vacation time is one of the perks and should be maximized, according to an article published in the American Medical Association’s AMA Wire<\/i>.<\/p>\n More Information<\/a><\/p>\n California Lawsuit Claims AbbVie Paid Doctors to Prescribe Humira<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — A lawsuit filed Tuesday in California claims that pharmaceutical company AbbVie used cash, gifts, and services to induce doctors to overprescribe the widely used drug Humira (adalimumab), ignoring the medicine’s potentially lethal side effects.<\/p>\n More Information<\/a><\/p>\n No Clear Benefit for Rivaroxaban After Hospital Discharge<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge, compared to placebo, according to a study published in the Sept. 20 issue of the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Global Prevalence of Insufficient Activity 27.5 Percent<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — In 2016 the age-standardized prevalence of insufficient physical activity was 27.5 percent, according to a study published in the October issue of The Lancet Global Health<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial<\/a><\/p>\n EPA Plan Will Maintain Carbon Emissions From Power Plants<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — The U.S. Environmental Protection Agency (EPA) has formally released its proposal to replace the Clean Power Plan with the Affordable Clean Energy Rule, which will keep carbon emissions from power plants constant, according to a report published by the American Thoracic Society.<\/p>\n More Information<\/a><\/p>\n Second HPV-Related Primary Cancers Common in Survivors<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — The risk of human papillomavirus-associated second primary cancers (HPV-SPCs) among survivors of HPV-associated cancers is significant, according to a study published online Sept. 7 in JAMA Network Open<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Patient Health Information Often Shared Electronically<\/font><\/p>\n WEDNESDAY, Sept. 19, 2018 (HealthDay News) — The most common electronically sent and received types of patient health information (PHI) include laboratory results and medication lists, according to a report published Aug. 15 by the U.S. Centers for Disease Control and Prevention’s National Center for Health Statistics.<\/p>\n Abstract\/Full Text<\/a><\/p>\n FDA Ad Campaign Hopes to Halt E-Cigarette Use Among Teens<\/font><\/p>\n TUESDAY, Sept. 18, 2018 (HealthDay News) — The U.S. Food and Drug Administration on Tuesday launched a new ad campaign aimed at curbing rampant e-cigarette use among American teens.<\/p>\n More Information<\/a><\/p>\n Scribes Improve Physician Workflow, Patient Interaction<\/font><\/p>\n TUESDAY, Sept. 18, 2018 (HealthDay News) — Use of medical scribes is associated with decreased physician documentation burden, improved work efficiency, and improved patient interactions, according to a study published online Sept. 17 in JAMA Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial<\/a><\/p>\n Review: Treatments for Primary Basal Cell Carcinoma Compared<\/font><\/p>\n TUESDAY, Sept. 18, 2018 (HealthDay News) — For patients with primary basal cell carcinoma (BCC), estimated recurrence rates are similarly low for excision, Mohs surgery, curettage and diathermy, and external-beam radiation, according to a review and meta-analysis published online Sept. 18 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n Drug Prices Increase More Than Expected After Shortages<\/font><\/p>\n TUESDAY, Sept. 18, 2018 (HealthDay News) — Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage, according to a research letter published online Sept. 18 in the Annals of Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Compliance With Requirement to Report Results on EUCTR Is Poor<\/font><\/p>\n TUESDAY, Sept. 18, 2018 (HealthDay News) — Half of trials on the European Union Clinical Trials Register (EUCTR) are non-compliant with the European Commission’s requirement that all trials post results to the registry within 12 month of completion, according to a study published online Sept. 13 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Use of Aspirin in Healthy Elderly Questioned in Three Studies<\/font><\/p>\n MONDAY, Sept. 17, 2018 (HealthDay News) — Low-dose aspirin appears to have limited effect on healthy life span in older people, according to three studies published online Sept. 16 in the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text 1<\/a><\/p>\n Abstract\/Full Text 2<\/a><\/p>\n Abstract\/Full Text 3<\/a><\/p>\n Association Health Plans Can Help Small Businesses Offer Coverage<\/font><\/p>\n MONDAY, Sept. 17, 2018 (HealthDay News) — Association health plans (AHPs) will provide small businesses with more choices, access, and coverage options, although critics warn that they may undermine the Affordable Care Act (ACA) marketplace, according to an article published in Managed Healthcare Executive<\/i>.<\/p>\n More Information<\/a><\/p>\n FDA Finds Another Carcinogen in Certain Valsartan Heart Meds<\/font><\/p>\n FRIDAY, Sept. 14, 2018 (HealthDay News) — The U.S. Food and Drug Administration warns that it has found a second impurity in three lots of Torrent Pharmaceuticals’ valsartan drug products.<\/p>\n More Information<\/a><\/p>\n FDA Approves Novel Treatment for Hairy Cell Leukemia<\/font><\/p>\n FRIDAY, Sept. 14, 2018 (HealthDay News) — Lumoxiti (moxetumomab pasudotox-tdfk) injection has been approved to treat certain instances of relapsed or refractory hairy cell leukemia (HCL), the U.S. Food and Drug Administration said yesterday.<\/p>\n More Information<\/a><\/p>\n Sales of Flavored E-Cigarette Products Up Since 2012<\/font><\/p>\n FRIDAY, Sept. 14, 2018 (HealthDay News) — Sales of flavored electronic cigarette products have increased dramatically since 2012, according to a study published online Aug. 23 in the U.S. Centers for Disease Control and Prevention’s Preventing Chronic Disease<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Situation Framing, Language Can Influence Decision-Making<\/font><\/p>\n FRIDAY, Sept. 14, 2018 (HealthDay News) — How a situation is framed and the language used to describe risks can influence patients’ decision-making, according to an article published in Physicians Practice<\/i>.<\/p>\n More Information<\/a><\/p>\n No Apparent Short-Term Cancer Risk From Recalled Valsartan<\/font><\/p>\n THURSDAY, Sept. 13, 2018 (HealthDay News) — Users of valsartan contaminated with N-nitrosodimethylamine (NDMA) seem not to have increased cancer risk, according to a study published online Sept. 12 in The BMJ<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial<\/a><\/p>\n Risks Posed by Spreading Oil and Gas Wastewater on Roads<\/font><\/p>\n THURSDAY, Sept. 13, 2018 (HealthDay News) — Spreading oil and gas (O&G) wastewaters on roads may pose human and environmental risks, according to a study recently published in Environmental Science & Technology<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Gains in Insurance Coverage Seen for Lesbian, Gay, Bisexual Adults<\/font><\/p>\n THURSDAY, Sept. 13, 2018 (HealthDay News) — Lesbian, gay, and bisexual (LGB) adults report continued problems affording care despite coverage gains offered by the Affordable Care Act, according to a study published in the August issue of Health Affairs<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n FDA Gets Tough on Juul, Other Electronic Cigarette Makers<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — Calling the use of electronic cigarettes a burgeoning epidemic among teens, the U.S Food and Drug Administration today announced a crackdown on the sale of Juuls and other flavored e-cigarette devices to minors.<\/p>\n Press Release<\/a><\/p>\n Statement From FDA Commissioner<\/a><\/p>\n At Least 15 Men Near Ground Zero Have Breast Cancer<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — At least 15 men who worked near Ground Zero after the 9\/11 attacks have been diagnosed with breast cancer, a New York City law firm claims.<\/p>\n CBS News<\/i> Article<\/a><\/p>\n Six-Step Analysis Can Help Improve Practice Logistics<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — A six-step analysis can help redesign and improve the outpatient health care process, according to a study recently published in the Journal of Evaluation in Clinical Practice<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Residents Working Long Hours Can Increase Alertness<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — Medical residents can take steps to maintain their energy and alertness during long shifts, according to an article published in the American Medical Association’s AMA Wire<\/i>.<\/p>\n More Information<\/a><\/p>\n Guideline-Discordant Prostate Cancer Imaging Up With Medicare<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — Patients with prostate cancer receiving care in a Medicare-only setting are more likely to receive guideline-discordant imaging, according to a study published online Aug. 17 in JAMA Network Open<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Propofol May Decrease Delay in Neurocognitive Recovery<\/font><\/p>\n WEDNESDAY, Sept. 12, 2018 (HealthDay News) — For older cancer patients undergoing major cancer surgery, propofol-based general anesthesia may reduce the incidence of delayed neurocognitive recovery versus sevoflurane-based general anesthesia, according to a study published in the September issue of the British Journal of Anesthesia<\/i>.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Rituximab + Lenalidomide Effective in Follicular Lymphoma<\/font><\/p>\n TUESDAY, Sept. 11, 2018 (HealthDay News) — Rituximab plus lenalidomide has similar efficacy to rituximab plus chemotherapy among patients with previously untreated follicular lymphoma, according to a study published in the Sept. 6 issue of the New England Journal of Medicine<\/i>.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Medicaid Work Requirements Don’t Impact Many Enrollees<\/font><\/p>\n TUESDAY, Sept. 11, 2018 (HealthDay News) — Medicaid work requirements will only impact a small proportion of persons and may only generate minimal savings, according to two research letters published online Sept. 10 in JAMA Internal Medicine<\/i>.<\/p>\n Abstract\/Full Text – Goldman<\/a><\/p>\n Abstract\/Full Text – Silvestri<\/a><\/p>\n