Inverse link seen for total MVPA, MVPA accumulated in bouts of \u226510 minutes with progression to CKD in overweight\/obese adults with T2D<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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WEDNESDAY, Feb. 7, 2024 (HealthDay News) — For adults with overweight\/obesity and type 2 diabetes (T2D), longer duration of moderate-to-vigorous physical activity (MVPA) and increases in MVPA are associated with a reduced risk for progression to chronic kidney disease (CKD), according to a study published online Feb. 6 in the British Journal of Sports Medicine<\/em>.<\/p>\n Mengyi Liu, from Nanfang Hospital in Guangzhou, China, and colleagues examined the long-term association of objectively measured MVPA and its longitudinal changes with progression to CKD in patients with T2D and overweight\/obesity in a study including 1,746 participants. MVPA was measured at baseline and years 1, 4, and 8.<\/p>\n In total, 567 participants experienced progression to CKD during a median follow-up of 12.0 years. The researchers observed a linear inverse association of cumulative average total MVPA and MVPA accumulated in bouts of \u00e2\u0089\u00a510 minutes with progression to CKD (per 100 minutes\/week higher amount: hazard ratios, 0.91 and 0.81, respectively). From baseline to year 4, an increase in total MVPA (fourth quartile; \u00e2\u0089\u00a563.2 minutes\/week) was associated with a reduced risk for progression to CKD compared with the largest reduction in MVPA (<\u00e2\u0088\u0092198.3 minutes\/week; hazard ratio, 0.67).<\/p>\n “Our study has important public health implications because it suggests that maintaining a high level of MVPA, regardless of length of the bout, may have renal benefit for adults with overweight\/obesity and T2D, especially for individuals who are unwilling or unable to engage in PA bouts that are \u00e2\u0089\u00a510min in duration,” the authors write.<\/p>\n