Meta-analysis of three COSMOS substudies shows evidence of benefits on global cognition, episodic memory<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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MONDAY, Jan. 22, 2024 (HealthDay News) — Daily multivitamin-mineral (MVM) supplementation yields cognitive benefits, according to a study published online Jan. 18 in the American Journal of Clinical Nutrition<\/em>.<\/p>\n Chirag M. Vyas, M.B.B.S., M.P.H., from Massachusetts General Hospital in Boston, and colleagues examined the effects of MVM supplementation on cognitive change using in-person, detailed neuropsychological assessments and conducted a meta-analysis to assess the MVM effects on cognition within the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) substudies. A total of 573 participants were included in the clinic subcohort of COSMOS (COSMOS-Clinic) who completed all cognitive tests administered at baseline. Nonoverlapping participants across three COSMOS substudies were included in the meta-analysis (COSMOS-Clinic [573 participants], COSMOS-Mind [2,158 participants], and COSMOS-Web [2,472 participants]).<\/p>\n The researchers found that over two years, there was a modest benefit for MVM versus placebo on global cognition in COSMOS-Clinic, with a significantly more favorable change in episodic memory but not in executive function\/attention. Clear evidence of the benefits of MVM on global cognition and episodic memory were seen in the meta-analysis of COSMOS substudies. The magnitude of the effect on global cognition was equivalent to a two-year reduction in cognitive aging.<\/p>\n “These findings will garner attention among many older adults who are, understandably, very interested in ways to preserve brain health, as they provide evidence for the role of a daily multivitamin in supporting better cognitive aging,” senior author Olivia Okereke, M.D., also from Massachusetts General Hospital, said in a statement.<\/p>\n The study was partially funded by Mars Edge, Contract Pharmacal Corp., and Pfizer Consumer Healthcare.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n