Fasting insulin and HOMA-IR values were increased with sleep restriction versus maintenance of adequate sleep<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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FRIDAY, Nov. 17, 2023 (HealthDay News) — Short sleep duration for six weeks impairs insulin sensitivity in women, according to a study published online Nov. 15 in Diabetes Care<\/em>.<\/p>\n Faris M. Zuraikat, Ph.D., from the Columbia University Irving Medical Center in New York City, and colleagues examined whether prolonged mild sleep restriction (SR), resembling real-world short sleep, impaired glucose metabolism in 36 women (11 postmenopausal), aged 20 to 75 years, without cardiometabolic diseases, with total sleep time of seven to nine hours\/night in a randomized crossover study. The study included two six-week phases: maintenance of adequate sleep (AS) and 1.5 hours\/night SR.<\/p>\n The researchers found that total sleep time was reduced by 1.34 \u00c2\u00b1 0.04 hours\/night with SR versus AS in linear models adjusted for baseline outcome values. With SR versus AS, fasting insulin and homeostasis model assessment of insulin resistance (HOMA-IR) values were increased; the effects on HOMA-IR were more pronounced in postmenopausal women. The effects of SR on glucose metabolism were not mediated by changes in adiposity; when changes in adiposity were included as a covariate, the results were not altered in the full sample.<\/p>\n “Clinicians should educate patients on the crucial role of sleep for health and discuss strategies to increase sleep duration, which may protect against IR and the development of type 2 diabetes, and promote healthy life span in women,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n