Decline in BP from high- to low-sodium diet was independent of hypertension status; generally consistent across subgroups<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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THURSDAY, Nov. 16, 2023 (HealthDay News) — Sodium reduction in the diet lowers blood pressure (BP), with the effect generally consistent across subgroups, according to a study published online Nov. 11 in the Journal of the American Medical Association<\/em> to coincide with the American Heart Association Scientific Sessions 2023, held from Nov. 11 to 13 in Philadelphia.<\/p>\n Deepak K. Gupta, M.D., from the Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues examined the distribution of within-individual BP response to dietary sodium. The study included prospectively allocated diet order with crossover in 213 community-based individuals (aged 50 to 75 years) who attended a baseline visit while consuming their usual diet and then completed one-week high- and low-sodium diets.<\/p>\n The researchers found that between high- and low-sodium diets, the median within-individual change in mean arterial pressure was 4 mm Hg, with no significant difference noted by hypertension status. In 73.4 percent of individuals, the low-sodium diet induced a decline in mean arterial pressure compared with the high-sodium diet. Overall, 46 percent of individuals were classified as “salt sensitive” based on a commonly used threshold of a 5 mm Hg or greater decline in mean arterial pressure between a high- and low-sodium diet. The mean systolic BP difference between individuals allocated to a high- versus low-sodium diet was 8 mm Hg at the end of the first dietary intervention week, which was mostly similar across subgroups. Adverse events were reported by 9.9 and 8.0 percent of individuals while consuming high- and low-sodium diets, respectively, and were mild.<\/p>\n “Sodium reduction significantly lowered BP in the majority of middle-aged to elderly adults in this study,” the authors write.<\/p>\n Abstract\/Full Text<\/a><\/p>\n