Vitamin D supplementation not an aid alone or in combination<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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WEDNESDAY, July 26, 2023 (HealthDay News) — The combination of aerobic and resistance exercises with computerized cognitive training may improve cognition in older adults with mild cognitive impairment (MCI), according to a study published online July 20 in JAMA Network Open<\/em>.<\/p>\n Manuel Montero-Odasso, M.D., Ph.D., from the Gait and Brain Lab at the Parkwood Institute in London, Ontario, Canada, and colleagues assessed whether aerobic-resistance exercises, computerized cognitive training, and vitamin D supplementation can enhance cognition among 175 older adults (aged 65 to 84 years) with MCI.<\/p>\n The researchers found that at six months, all active intervention arms with aerobic-resistance exercise, regardless of the addition of cognitive training or vitamin D, significantly improved the Alzheimer Disease Assessment Scale Cognitive 13 (ADAS-Cog-13) score versus control (mean difference, \u00e2\u0088\u00921.79 points). Exercise and cognitive training significantly improved the ADAS-Cog-13 score compared with exercise alone (mean difference, \u00e2\u0088\u00921.45 points). There was no significant improvement seen with vitamin D supplementation.<\/p>\n “In this clinical trial, older adults with MCI receiving aerobic-resistance exercises with sequential computerized cognitive training significantly improved cognition, although some results were inconsistent. Vitamin D supplementation had no effect,” the authors write. “Our findings suggest that this multidomain intervention may improve cognition and potentially delay dementia onset in MCI.”<\/p>\n One author disclosed ties to the pharmaceutical industry.<\/p>\n