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WEDNESDAY, Sept. 5, 2018 (HealthDay News) — For patients with stable chest pain, coronary computed tomographic angiography (CTA) results in a lower rate of death from coronary heart disease or non-fatal myocardial infarction at five years, according to a study published in the Sept. 6 issue of the New England Journal of Medicine<\/i>.<\/p>\n
David E. Newby, M.D., from the University of Edinburgh in the United Kingdom, and colleagues randomized 4,146 patients with stable chest pain who had been referred to a cardiology clinic for evaluation to either standard care plus CTA or standard care alone in a 1:1 ratio. Patients were followed for a median of 4.8 years, with 20,254 patient-years of follow-up.<\/p>\n
The researchers found that the five-year rate of the primary end point (death from coronary heart disease or non-fatal myocardial infarction at five years) was lower in the CTA versus the standard-care group (2.3 versus 3.9 percent; hazard ratio, 0.59). In the first few months of follow-up, the rates of invasive coronary angiography and coronary revascularization were higher in the CTA group; however, overall rates were similar at five years. More preventive therapies and antianginal therapies were initiated in patients in the CTA group (odds ratios, 1.40 and 1.27, respectively).<\/p>\n
“The use of CTA in addition to standard care in patients with stable chest pain resulted in a significantly lower rate of death from coronary heart disease or non-fatal myocardial infarction at five years than standard care alone,” the authors write.<\/p>\n
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