Association seen between energy adjusted dietary inflammatory index score and fluid-attenuated inversion recovery lesion volume<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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MONDAY, June 26, 2023 (HealthDay News) — For people with multiple sclerosis (MS), a pro-inflammatory diet is associated with worsening relapse rate and greater periventricular fluid-attenuated inversion recovery lesion volume, according to a study published online May 6 in Multiple Sclerosis Journal<\/em>.<\/p>\n Alice M. Saul, from the University of Tasmania in Australia, and colleagues examined whether Dietary Inflammatory Index (DII) scores correlate with measures of MS progression and inflammatory activity. A total of 223 participants with a first clinical diagnosis of central nervous system demyelination were followed annually for 10 years. DII and energy-adjusted DII (E-DII) scores were calculated at baseline and at five- and 10-year reviews and assessed as predictors of relapses and annualized change in disability, and two magnetic resonance imaging measures were also performed and assessed.<\/p>\n The researchers found that the risk of relapse was higher with a more pro-inflammatory diet (highest versus lowest E-DII quartile: hazard ratio, 2.24). An association between E-DII score and fluid-attenuated inversion recovery lesion volume was evident when analyses were limited to those assessed on the same manufacturer of scanner and those with a first demyelinating event at study entry (\u00ce\u00b2 = 0.38).<\/p>\n “While an anti-inflammatory diet does not replace anti-inflammatory medications in MS, this study provides evidence that an anti-inflammatory diet could contribute to the health and well-being of people with MS,” the authors write.<\/p>\n One author disclosed ties to Connecting Health Innovations, a company that has licensed the right to his invention of the Dietary Inflammatory Index (DII\u00c2\u00ae).<\/p>\n