Women with a normal weight first child and small second infant have increased risk of cardiovascular mortality<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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FRIDAY, June 16, 2023 (HealthDay News) — Changes in offspring birthweight quartiles from first to second pregnancy could inform women’s future risk of cardiovascular disease (CVD) death, according to a study published online May 30 in the American Journal of Epidemiology<\/em>.<\/p>\n Yeneabeba Tilahun Sima, Ph.D., from the University of Bergen in Norway, and colleagues assessed long-term CVD mortality by offspring birth weight patterns among women with spontaneous and iatrogenic term deliveries in Norway (1967 to 2020). <\/p>\n The researchers found that changes in offspring birth weight quartiles were associated with long-term maternal CVD mortality. Women with a first offspring in quartile 2\/3 (Q2\/Q3) and a second in quartile 1 had higher mortality risk (hazard ratio [HR], 1.33; 95 percent confidence interval [CI], 1.18 to 1.50), compared with women who had two term infants in Q2\/Q3. Risk of CVD mortality was lower if the second offspring was in quartile 4 (HR, 0.78; 95 percent CI, 0.67 to 0.91). Having a second offspring in quartile 4 offset the risk associated with having a first infant in quartile 1 (HR, 0.99; 95 percent CI, 0.75 to 1.31). These patterns were similar regardless of iatrogenic or spontaneous deliveries.<\/p>\n “Our findings highlight the importance of including information from women’s subsequent births for identification of high-risk subgroups for specific follow-up,” the authors write.<\/p>\n