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Cigarette Smoking a Risk Factor for Heart Failure in Blacks

Current smoking linked to higher mean LV mass index, lower mean LV circumferential strain

MONDAY, April 16, 2018 (HealthDay News) — Cigarette smoking is a risk factor for left ventricular (LV) hypertrophy, systolic dysfunction, and incident heart failure hospitalization in blacks, according to a study published online April 16 in Circulation.

Daisuke Kamimura, M.D., Ph.D., from the University of Mississippi Medical Center in Jackson, and colleagues examined 4,129 black participants (2,884 never smokers, 503 current smokers, and 742 former smokers) without a history of heart failure or coronary heart disease at baseline in the Jackson Heart Study. The relationships between cigarette smoking and LV structure and function were investigated using cardiac magnetic resonance imaging, brain natriuretic peptide levels, and incident heart failure hospitalization.

The researchers found that, compared with never smoking, current smoking was associated with higher mean LV mass index and lower mean LV circumferential strain after adjustment for confounding factors (P < 0.05 for both). There were correlations for smoking status, intensity, and burden with higher mean brain natriuretic peptide levels (all P < 0.05). There were 147 incident heart failure hospitalizations over a median follow-up of eight years. After adjusting for traditional risk factors and incident coronary heart disease, current smoking, smoking intensity among current smokers, and smoking burden among ever smokers were significantly associated with incident heart failure hospitalization when compared with never smoking.

“In blacks, cigarette smoking is an important risk factor for LV hypertrophy, systolic dysfunction, and incident heart failure hospitalization even after adjusting for effects on coronary heart disease,” the authors write.

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