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CPAP Non-Adherence Tied to CV, All-Cause Hospital Readmissions

Difference in 30-day pulmonary-cause readmissions not significant

THURSDAY, March 1, 2018 (HealthDay News) — Non-adherence to continuous positive airway pressure (CPAP) is tied to higher rates of hospital readmission for patients with obstructive sleep apnea (OSA), according to a study published in a recent issue of the Journal of Clinical Sleep Medicine.

Kimberly K. Truong, M.D., from University of California Irvine, and colleagues retrospectively reviewed medical records of patients with OSA hospitalized at a Veterans Affairs Hospital (2007 to 2015) in order to assess the role non-adherence to CPAP plays in outcomes. Analysis included 345 patients (183 adherent and 162 non-adherent).

The researchers found that the adherent group had 215 initial admissions versus 268 index admissions in the non-adherent group. The non-adherent group had a significantly higher 30-day all-cause readmission rate (adjusted odds ratio [aOR], 3.52; 95 percent confidence interval [CI], 2.04 to 6.08; P < 0.001) and 30-day cardiovascular-cause readmission rate (aOR, 2.31; 95 percent CI, 1.11 to 4.78; P = 0.024). However, there was no significant difference in 30-day pulmonary-cause readmissions (aOR, 3.66; 95 percent CI, 0.41 to 32.76; P = 0.25).

“Non-adherence to CPAP is associated with increased 30-day all-cause and cardiovascular-cause readmission in patients with OSA,” the authors write. “Ensuring CPAP adherence is crucial in addressing general and cardiovascular-related health care utilization and morbidity in patients with OSA.”

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